UCSC BME 200 Fall 2005

Being a Bioinformatics Grad Student

(Last Update: 10:01 PST 7 December 2005 )
This is a required course for graduate students in bioinformatics.

For catalog copy and pre-requisites, see the main page for BME200.

Who, When, and Where:

Instructor: Kevin Karplus ( karplus@soe.ucsc.edu) http://www.soe.ucsc.edu/~karplus
Office hours: M 3:30-4:40 315B Baskin Engineering

lecture and discussion section (REQUIRED): Crown 105 Th 4-5:45

Do not take BME 200 for a letter grade!

The lectures and discussions will cover topics specific to bioinformatics, including such things as lab safety and cultural differences between the academic cultures of biology and computer science, as well as more general graduate student stuff, such as how to write a research paper, avoiding sexual harassment, fellowships, library usage, LaTeX, ...

All new grad students should plan on taking 280B this quarter, since it will be a series of introductory lectures by faculty who can accept grad students into their labs for lab rotation projects.

Requirements to pass

There will be a small number of written assignments for this class: a LaTeX exercise, a library/BibTeX exercise, writing a fellowship or grant proposal, and a web page exercise.

The course is graded strictly on the Satisfactory/Unsatisfactory scale. Do not register for a letter grade.

Texts

Required: Optional:

Academic Integrity

Anyone caught cheating in the class will be punished severely—most likely failed in the class and possibly thrown out of grad school.

Cheating includes any attempt to claim someone else's work as your own. Plagiarism in any form (including close paraphrasing) will be considered cheating. Use of any source without proper citation will be considered cheating.

Collaboration without explicit written acknowledgment will be considered cheating. Collaboration on some assignments with explicit written acknowledgment is encouraged—guidelines for the extent of reasonable collaboration will be given in class.

Tentative schedule of topics

Note: list should be updated throughout the quarter to reflect what really happens.
22 Sept 05
Administrivia.
Organization of SoE and bioinformatics file systems. Permissions and user groups. Where things are kept, how to get access to cluster computing, Go through .cshrc file to indicate what things people might want to set up for themselves.
29 Sept 05
Using a Makefile and gnumake to run LaTeX, BibTeX, dvips, and distill.

Preparing a document with LaTeX
Homework assignment: LaTeX assignment Due 13 Oct 2005.

The purpose of this assignment is to develop some preliminary facility with LaTeX, particularly with math equations and tables. You are to try to duplicate (approximately) the 2-page paper in latex-assign.pdf

There are some examples of a basic LaTeX paper in example.tex and the corresponding output example.pdf. You can use "make" to do the repeated calls to latex with the Makefile

Turn in both the .tex source and the printed output by 13 October 2005.

6 Oct 05
Lab safety (with some ergonomics) Brent Cooley, EHS Homework assignment: fellowship application Due 20 Oct 2005.
13 Oct 05
Funding opportunities. Expectations of a GSR. Writing a fellowship application.

Being a TA: Running discussion sections, workload, TA union and strikes. Brief mention of AAUP and their publication Academe, which is available on-line as http://www.aaup.org/publications/Academe/
Academic integrity: TA responsibilities for detecting, reporting, and enforcing.

20 Oct 05
Rita Walker Sexual Harrassment/Title IX.

What goes into a paper? Structure, cultural expectations, length, writing style, ... Who is an author? When do you cite?

Writing proposals (thesis proposals, funding applications, ...) Funding sources.
Example of a great thesis proposal by Rachel Karchin. (Postscript file Portable Document Format file; both only available from Baskin School of Engineering computers.)

27 Oct 05
Pictures in papers: Advanced LaTeX
BibTeX: citation databases in LaTeX.
Homework assignment: LaTeX/BibTeX assignment Due 10 17 Nov 2005.
Incidentally, it would be a good idea to use the existing database in /projects/compbio/papers/tex/all.bib, by using
setenv BIBINPUTS .:/projects/compbio/papers/tex::
in your .cshrc file, and saying \bibliography{all,my} to include both your file my.bib and /projects/compbio/papers/tex/all.bib in your search for bibliography entries.
3 Nov 05
Oral presentation. How to design your slides (Powerpoint, keynote, LaTeX+acroread). How to speak loudly.
Poster presentation. How to prepare and print a poster, design guidelines.
10 Nov 05
Videotaping of short oral presentations.
17 Nov 05
Setting up a web page, General discussion on presentation of data. Advertising for reading Envisioning Information.

Discussion with visitor Jerry Tsai.

Homework assignment: Web page assignment Due 1 Dec 05

24 Nov 05
Thanksgiving---no class
1 Dec 05
Instructor evaluation.

general discussion of courses for winter quarter, lab rotations, master's thesis, ...

Wed 7 Dec 05 8am-11am
Final exam slot (not used)

Useful resources



slug icon to go to Scool of Engineering home page
SoE home
sketch of Kevin Karplus by Abe
Kevin Karplus's home page
BME-slug-icon
BS, MS, and PhD programs
BME 200 home page Karplus's lab page UCSC Bioinformatics research

Questions about page content should be directed to

Kevin Karplus
Biomolecular Engineering
University of California, Santa Cruz
Santa Cruz, CA 95064
USA
karplus@soe.ucsc.edu
1-831-459-4250